When was this clue last seen?

This clue last appeared in the NYT Crossword on Monday, 25 April 2022.

Pigment giving color to skin

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pigmentgivingcolor

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This clue appeared in the NYT Crossword on Monday, 25 April 2022. The answer MELANIN is a 7-letter entry.

What is the answer to "Pigment giving color to skin"?: MELANIN
How many letters is the answer to "Pigment giving color to skin"?: The answer has 7 letters.
When was this clue last seen?: This clue last appeared in the NYT Crossword crossword on Monday, 25 April 2022.
Has this crossword clue appeared before?: This appears to be a rare or unique clue.

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